This Duke Clinical Research Institute (DCRI) NIH "Rethinking Clinical Trials" Grand Rounds features Harlan M. Krumholz, MD, SM, Harold H. Hines, Jr. Professor of Medicine and Public Health at Yale University, and Joseph S. Ross, MD, MHS, Professor of Medicine and Public Health at Yale University. Drs. Krumholz and Ross will discuss " Is It Time to Embrace Preprints? A Conversation About the First 18 Months of medRxiv".