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KL2 Visiting Scholar Seminar Series: Differences in the Cervicovaginal Microbiomes of Women Who Naturally Control HIV Progression

Date Tue, Aug 25
Time 12: 00 PM - 1: 00 PM
Location Online

As a part of the Virginia Commonwealth University (VCU) Wright Center KL2 Visiting Scholar Seminar Series, GHUCCTS KL2 scholar Dr. Katherine G. Michel, PhD, MPH will give a keynote presentation titled "Differences in the Cervicovaginal Microbiomes of Women Who Naturally Control HIV Progression". This webinar is free and open to the public.

ABSTRACT: Much research has focused on understanding the etiology of how a small percentage of HIV-positive people naturally control HIV viral levels without using antiretroviral medications. HIV-positive controller status does not seem to associate with demographic, social, or behavioral factors, nor does it develop through infection with replication- incompetent HIV. Data suggest HIV-positive controllers have unique immune phenotypes and gut microbiome compositions, however little research has focused on the potential role of other mucosal microbiomes. Our preliminary data suggest altered cervicovaginal microbiomes in women who naturally control HIV, particularly elevated populations and increased genetic diversity of key Lactobacillus sub-species.

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