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KL2 Junior Faculty Scholars Program

Request for Applications

With support from a Clinical and Translational Science Award from the NIH National Center for Advancing Clinical and Translational Science (NCATS), we are pleased to announce the next round of applications for our Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) KL2 award.  This  K-series  career  development award  is  nearly identical to our previous KL2 awards and analogous to individual  K23 or K08 awards, with a focus on developing early-career (MD or equivalent; doctorally-trained  nurses, pharmacists or dentists; and clinically or translationally-oriented  PhD)  faculty  investigators  through  an  inter- or multi-disciplinary  mentored  research experience so that they can become independent, extramurally-funded investigators. Given the goals of the GHUCCTS, awards will favor those: 1) who propose novel trans-, inter-, or multi-disciplinary and collaborative research projects, 2) from the entire T1-T4 translational continuum, 3) which span departments, disciplines, and institutions, and 4) address significant health disparities.

The program will require a documented commitment of 75% protected time for research and career development activities and will provide salary support (we anticipate up to $90,000 of salary, supplemented by fringe benefits).  In addition, we anticipate that the program will provide up to $40,000/year to support research and training.  We anticipate that support will be provided for up to 3 years; with 2 years by GHUCCTS (based upon documented progress and continued promise), and 1 year fully cost-shared by the sponsoring department or institution.  

CTR Scholars will be expected to submit individual K- or R-series (R01, R21 applications or their equivalent) applications within 2 years of the award and, if successful, must then be provided with a firm continued commitment of 75% protected time and salary from their sponsoring departments (i.e., for at least 5 years from the date of original appointment to the KL2 or for duration of the R-series award, whichever is shorter) in order to ensure their success.

We envision a quick application and review process in order to enable us to appoint one KL2 awardee in April 2018. To allow for this rapid review cycle, we encourage potential applicants to contact us as soon as possible to clarify requirements and suitability of this support mechanism for your career development goals in order to submit the pre-application by the deadline. 

 

ELIGIBILITY:
  • All candidates must be US citizens, Non-Citizen Nationals, or Permanent Residents
  • All candidates must have a full-time faculty or equivalent appointment at a GHUCCTS institution (Georgetown University, Howard University, or MedStar Health) at the time of award activation
  • Must devote 75% effort to the program for a full 3 years (will consider 50% effort, with prior consultation and approval, in accord with NIH guidelines, for some surgeons or procedural subspecialists
  • Individuals who were, or currently are Principal Investigator of NIH R01, R29, P01, K01, K08, K22 and K23 grant ARE NOT eligible

PRE-APPLICATION:

Anyone planning to submit an application in response to this RFA should complete and submit the Pre-Application Form (online) by September 15, 2017 in order to ensure that the planned application will be responsive.  

SUBMIT ONLINE PRE-APPLICATION

FINAL APPLICATION REQUIREMENTS:  

  •  An 8-10 page research proposal for the major research project, describing three (3) years of work. Using the PH398  (current  R01)  format,  including:  specific  aims  page,  significance,  innovation,  and  approach, providing background, major experimental or study details, with attention to feasibility, available resources and collaborations, and plans for subsequent work.  While the focus is on the major research project, please describe other planned research activities and sources of support required for their completion in order to account for 75% FTE that will be devoted to the K award.
  • A  brief (1-3 page) plan describing a subsequent individual K award application or R01 application that would be submitted in year 1 or 2 of the KL2 period of support and how that application would be made more competitive by prior KL2 support. 
  • A 1-page statement detailing 3-year and 5-year career plans as well as the specific role of this mentored research experience in achieving those goals, and the manner in which the project and mentorship plans will specifically advance multi- or inter-disciplinary research.
  •  A 2-4 page proposal detailing the plan and rationale for specific didactic training to supplement and enhance the mentored research experience.  In particular, please provide a critical self-appraisal of current skills and needs for further training with respect to the  core competencies for translational identified by NCATS.  If a specific degree or certificate program is proposed, please provide details and rationale.  We encourage applicants to consider including coursework from the GHUCCTS MS program in Clinical and Translational research in the didactic educational plan if appropriate.   If specific courses, workshops, internship, or tutorial experiences are proposed, please provide details and rationale.
  • New NIH biosketch format (for the applicant and each mentor)
  • A three-year detailed budget & budget justification (using NIH’s FP4 & FP5 forms)
  • A detailed letter from the department chair (co-signed by any other relevant responsible official) endorsing and appraising the applicant and the application, as well as outlining the department’s plan for, and commitment to, the applicant.  LETTER MUST INCLUDE:
    • Specific plan that guarantees 75% protective time from day 1 of KL2 support
    • Details of all past and current institutional research support (e.g., protected time, research funds, non-monetary resources) provided to the applicant 
    • Plans for additional/continued institutional research support during the 3 years as a KL2 scholar
    • Details regarding provision of, or access to adequate research facilities, ancillary, or core resources required for the proposed research
    • Details  regarding  ALL  anticipated clinical, teaching, administrative, or other  activities  which  might  be  reasonably  construed  as either extraneous to (or competing with) research career development
    • Commitment to continue this support for 5 years (from the date of initial appointment) if the applicant transitions successfully to an individual K-series or R01/R21 award following the  period of KL2 support.
  • A letter from the mentor(s). LETTER MUST INCLUDE:  
    • Mentors letters can be written individually, or all mentors may contribute to a single letter which, however, must delineate each of their roles as well as the plan for coordinated joint mentorship
    • Detailed commitment to the applicant
    • Their plans for interacting with the applicant over the next 3 years, as well as an appraisal of the applicant's likelihood of productivity and success in transitioning to research independence.
  • One to two additional  letters  of  support  by  senior  faculty  familiar  with the  applicant’s  current  work  and accomplishment and able to evaluate the likelihood of success, defined by the transition to individual extramural research funding.

Mentor Qualifications:   

Mentors must interact closely with the scholar, and should have research expertise and experience relevant to the proposed career development program. Mentors must be committed to continue their involvement throughout the total period of the scholar’s career development under this award. Each Scholar candidate appointed in the program award must have a primary mentor, preferably from a GHUCCTS institution, who: (1) has a track record of successful and sustained federal (i.e., NIH, AHRQ, CDC, FDA, DOD, HRSA or VA) research funding, (2) has the research resources (including funding, facilities, space, collaborations, access to key populations, technologies, and reagents) to ensure productivity, and 3) has a track record of successful mentorship of trainees who have gone on to productive independent academic careers. The mentor must be committed to continue this involvement throughout the candidate's total period of development under the award.  Secondary or joint mentors should be similarly committed to the scholar’s career development, but provide complementary perspectives, guidance, and support.  For example, joint mentors should be expert in demonstrably-differing disciplines or specialties than the primary mentor or focus their research in differing parts of the clinical-translational research continuum (T1-T-4).  The applicant and mentors must explain the rationale for selection of the mentoring team and how it will function to guide the applicant to independent funding, translational research productivity, and successful academic career development. 

 

DEADLINES:

  • Complete application due by 11:59 PM ON  JANUARY 8, 2018
  • Submit Final Application in PDF format to Ms. Cyndi Campbell narcissc@georgetown.edu

 AWARD NOTIFICATION:

  • Anticipated award notification:  April  2018  

Inquiries:

Scientific & Research Contacts:

   Jason G. Umans, MD, PhD: jason.umans@gmail.com

   Dexter L. Lee, PhD: dllee@howard.edu

   Kathryn Sandberg, PhD: sandberg@georgetown.edu


Administrative Contact

   
   Cyndi Campbell, MBA: 
narcissc@georgetown.edu